Roth was born in 1903 as son of Adolf and Ida Roth-Obrecht in Wangen on the Aare. He really wanted to be a painter. After attending the Gymnasium in Solothurn, he decided to study mechanical engineering. After only one semester, he switched to architecture. During his free time, however, he was engaged in painting. From 1922 studied Alfred Roth Architecture at ETH Zurich and graduated in 1926 with a diploma in Professor Karl Moser . He applied to his studies at the Bauhaus , but was through the mediation of Prof. Moser 1927-1928 employees in the Paris studio of Le Corbusier and Pierre Jeanneret .
He worked for Le Corbusier and Pierre Jeanneret in Paris at the Völkerbundpalast project for Geneva and later became Le Corbusier's construction manager. He built at this time u. A. The two Corbusier -Houses of Weissenhofsiedlung in Stuttgart. He was also influenced by Corbusier's work later on. His work was strongly influenced by the artist Piet Mondrian influenced, he also knew personally. According to him, he had a real Mondrian in his possession. He collected the art of his time.
In 1928 he planned his first own building. It was a warehouse for the familienigene Pferdehaarspinnerei in Wangen, which was however only 1929 executed. Also in 1928 he opened his first own office in Göteborg with the architect Ingrid Wallberg. Two years later he returned to Switzerland, where he in 1932 an office in Zurich in joint studio with his cousin Emil Roth opened.
1935-1936 built Roth along with Emil Roth and Marcel Breuer the Doldertalhäuser in Zurich, which remained the style of Le Corbusier true: The two apartment buildings are on stilts, and the floor plans follow the plan libre. In the following years, Roth dealt extensively with public buildings, especially school buildings, and realized numerous projects in the Middle East.
A bed design was created in 1927; For a long time he was mistakenly called the Corbusier bed. However, Alfred Roth had developed the prototype because he needed a sliding bed with runners for a niche.
He was visiting professor at the Washington University in St. Louis, 1953 at the Harvard University in Cambridge, MA and 1951/57? Until 1971, professor at the ETH Zurich. Roth was honorary doctorate from the Technical University of Munich and the Istituto Universitario di Architettura (Venice). Alfred Roth also gave lectures at universities and architectural schools and attended architecture studying in his house. The students could work and live there.
In the early 1980s he supported the proposal of the State Academy of Fine Arts in Stuttgart , the adjacent, in need of renovation Weissenhofsiedlung , at least in the future to use parts of the building ensembles by the university, but rejected a plan approved by the city of Stuttgart the state of Baden-Württemberg has been. His project proposal "Complements of the 'Weissenhof-Siedlung' in Stuttgart" from 1981 went completely in line with the idea of a campus extension of the university.
1984 appointed him the State Academy of Fine Arts Stuttgart an honorary member. Alfred Roth died in Zurich in 1998, his grave is in Wangen an der Aare.